Surviving each run in Risk of Rains Returns can be a bit tricky if you’re not familiar with certain unlockable items and modifiers like Artifacts. These powerful modifiers can make your roguelike campaign much more interesting, and sometimes hassle-free. There are 14 Artifacts for players to get their hands on, each with unique effects that last for the entirety of your run in the game.

However, you’ll find Artifacts just as hard to find in Risk of Rain Returns. Since you only need to unlock them once to use them in one of your future runs, knowing where to find them can save you some time. So if you’re looking for unique effects and want to know the locations of all these powerful items, here’s a guide that you should check out.

Here's a list of all Risk of Rain Returns artifacts and their locations:

That's all this guide will cover. For more interesting guides like this one, check out our dedicated Video Game Guides section, right here on Gamer Tweak.