You’ll need a solid build in Hades 2 if you want to have a chance at beating Chronos. Duo Boons offer just that: these incredibly rare upgrades greatly enhance Melinoe’s potential. There are 56 Duo Boons in total. Let’s rank the top 10 that can change a build for the better.
Hades 2 – Best Weapon & Blessing Combo in the Game – Get the MOST POWERFUL build on every run – Full Guide!
To get a Duo Boon in Hades 2, you need to have all the required Boons from both gods involved, then get lucky on your next find. You'll know a Duo Boon is active if both gods appear to be conversing with Melinoë before offering it. "The Queen" Arcana can help give you a small percentage bonus for seeing this.
While Duo Boons are fun to get in the wild, some are good enough to build towards right away. That said, make sure you have a backup plan in case the gods are stingy and don’t show you a Duo Boon.
Once you've performed the Insight into Offerings Incantation, you can see what requirements the Duo Boons have by pressing the "Insight" key (Y on Xbox Controller, I on Keyboard). You can then use Keepsakes to guarantee your chosen god and maximize your chances of finding these synergies.