Diablo 4 has one of the longest campaigns in the dungeon crawler series, though there are plenty of side quests scattered throughout Sanctuary. In Desperate Times, there's a side quest you can pick up in the Imperial Library of Kehjistan.
How to Ask the Watcher for Help in Diablo 4 – In Desperate Times Quest
Before you can start this quest to gain XP, gold and fame, you must meet a requirement. You cannot start this side quest until you have fully completed the main campaign and returned to Kehjistan.
While this is a relatively simple quest that only took me a few minutes to complete, players have reported difficulty requesting help from the watcher. Since this is the central premise of the entire side quest, performing this action is essential, but it can be unclear how exactly to signal this NPC.
To start the "In Desperate Times" quest in Diablo 4, you'll need to travel to the Imperial Library waypoint in Kehjistan. From here, you can interact with the nearby book on top of the shelf titled "On Caldeum's Defenses" to start the quest.