Whether you're trying to explore, fight, or find a treasure chest on top of a cliff, No Rest for the Wicked is a tough game from start to finish.
From Rats & Raiders Quest Guide in No Rest for the Wicked
And the difficulty doesn’t magically drop when you tackle side quests like Of Rats and Raiders in No Rest for the Wicked. This quest in particular can take you three to five hours to complete, and isn’t as easy as Winnick makes it sound. That said, it’s the only way to unlock housing in the game, so it’s not one you should skip. In this guide, I’ll show you how to start and complete every step of Of Rats and Raiders in No Rest for the Wicked.
After arriving in Sacrament, go to the upper left corner of the city where Odessa is being held captive. There you will meet Winnick, who will tell you all about your mission.
The first step to completing Of Rats and Raiders is finding Darak, the leader you must confront.