Wiring a single amplifier can be complicated enough, especially if you’re dealing with a factory car stereo. Things get even more complicated when you add multiple amplifiers to the equation. You can wire two amplifiers or multiple amplifiers into a single car audio system, but that takes extra planning.

The most important factors to consider when connecting two or more amplifiers are how to handle the power cord, the grounding of each amplifier, and whether the external turn-on signal from your head unit is strong enough to split across multiple amplifiers.

The short answer is that you can use any number or combination of power amplifiers in a car audio system as long as you connect them properly. The most important requirement is that the charging system must be able to supply enough current in the first place. If you add too many amplifiers and they draw too much current, you may need to upgrade your alternator or install a reinforcement cap.

Whether it's better to use a single multi-channel amplifier or multiple amplifiers to power your various speakers depends on factors such as available space, desired results, the amplifier classes you use, and personal preference.