There are a ton of different errors to watch out for in League of Legends, but some players are running into a new bug in Vanguard: error 185.
How to Fix League of Legends Vanguard Error 185 – Working FIX
Error 185 prevents you from connecting to games or getting into the game itself, forcing you to restart your process and close the game entirely. This is also an error that occurs with the game’s kernel-level anti-cheat, Vanguard.
However, this is a completely different error that has a specific reason for its triggering, and can be fixed with a few different steps. Here is how to fix League's Vanguard Error 185.
According to Riot Games, League of Legends Error 185 is most likely caused by the client being left running for more than seven days, or by being logged into the client on multiple devices. As a result, you should be able to resolve this error by logging out and back into the client. You should also close all instances of League or the game client from your Task Manager.