Mfc100u.dll errors are caused by situations that lead to the removal or corruption of the mfc100u DLL file, a key component of the Visual C++ runtime library provided by Microsoft.
How to Fix the 'MFC100U.DLL is Missing' Error
Follow these steps in the order they are listed below to try the simpler solutions first.
Download and run the Microsoft Visual C++ 2010 Service Pack 1 Redistributable Package MFC Security Update. This will replace/restore the mfc100u.dll with the most recent copy provided by Microsoft.
Microsoft offers you several download options for this update depending on the version of Windows that you have installed: x86 (32-bit) or x64 (64-bit).