Tyrael's Might is an Uber Unique chest armor in Diablo 4 that can be obtained in Uber Boss fights or crafted at the Alchemist with Resplendent Sparks. It's most useful for Whirlwind Dust Devil Barbarians, though its great defensive affixes are useful for other classes as well.
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Tyrael's Might is in the boss loot tables for Andariel and Duriel in Diablo 4 season four, so these bosses can drop this chest armor piece when you defeat them. The other way to get it is to craft it from the Alchemist in the Transmutation menu for four Resplendent Sparks and 50 million gold, which is a guaranteed but expensive way to obtain it.
You can only fight Andariel or Duriel if you are in World Tier Four. To summon Andariel, go to the Hanged Man's Hall dungeon in Tarsarak and use two Sandscorched Shackles and two Pincushioned Dolls to activate the Altar of Anguish. These items can be dropped by World Bosses. If you want to fight Duriel instead, go to the Gaping Crevasse in Kehjistan and summon him using two Mucus-Slick Eggs, obtained from Echo of Varshan, and two Shards of Agony, obtained from Grigoire or dropped by World Bosses.
It's hard to get Tyrael's Might randomly from Uber Bosses, so you might find it easier to farm gold and save Uber Uniques for Resplendent Sparks. You'll need to kill some Uber Bosses for Uber Uniques anyway, so you might get lucky and get Tyrael's Might while you're there.