Is SS sickle cell?

Hemoglobin SS disease is the most common and most severe type of sickle cell disease. It occurs when you inherit the hemoglobin S gene mutation from both parents. In this type, the body only produces hemoglobin S. This type is often called “sickle cell anemia.”

What are other names for sickle cell disease?

Sickle cell disease is also known as:

• HbS disease.
• Hemoglobin S Disease.
• SCD.
• Sickle cell disorders.
• Sickling disorder due to hemoglobin S.

What type of disorder is sickle cell anemia?

Sickle cell anemia is one of a group of disorders known as sickle cell disease. Sickle cell anemia is an inherited red blood cell disorder in which there aren’t enough healthy red blood cells to carry oxygen throughout your body. Normally, the flexible, round red blood cells move easily through blood vessels.

What is the scientific name for sickle cell anemia?

Also known as Sickle Cell Anemia, Hemoglobin S or SS disease, Sickling disorder due to hemoglobin S.

What are the four types of sickle cell disease?

There are several types of sickle cell disease. The most common are: Sickle Cell Anemia (SS), Sickle Hemoglobin-C Disease (SC), Sickle Beta-Plus Thalassemia and Sickle Beta-Zero Thalassemia.

What blood group is sickle cell?

The condition is often treated with regular blood transfusions so subtypes, such as Ro, are important in ensuring patients get blood which is most compatible with their blood type and subtype. Many people with sickle cell have the Ro subtype.

Which blood type is special?

However, in the United States, AB-negative is considered the rarest blood type, and O-positive is the most common. The Stanford School of Medicine Blood Center ranks blood types in the United States from rarest to most common as follows: AB-negative (. 6 percent)

What triggers sickle cell?

Sickling may be triggered by conditions associated with low oxygen levels, increased blood acidity, or low blood volume. Common sickle cell crisis triggers include: sudden change in temperature, which can make the blood vessels narrow. very strenuous or excessive exercise, due to shortage of oxygen.

Who first discovered sickle cell disease?

A Brief History of Sickle Cell Disease. “Peculiar elongated and sickle-shaped” is how sickle cells were first described in 1904 by intern Ernest Edward Irons when examining the blood of Walter Clement Noel, a 20-year-old first-year dental student from a wealthy Black family in Grenada.

How did sickle cell begin?

SCD originated in West Africa, where it has the highest prevalence. It is also present to a lesser extent in India and the Mediterranean region. DNA polymorphism of the beta S gene suggests that it arose from five separate mutations: four in Africa and one in India and the Middle East.

When did sickle cell disease start?

Sickle cell disease (SCD) was first described in 1910, in a dental student who presented with pulmonary symptoms (1). Herrick coined the term “sickle-shaped” to describe the peculiar appearance of the rbc of this patient (Figure ​

Where is sickle cell most common?

Sickle cell disease (SCD) affects millions of people throughout the world and is particularly common among those whose ancestors came from sub-Saharan Africa; Spanish-speaking regions in the Western Hemisphere (South America, the Caribbean, and Central America); Saudi Arabia; India; and Mediterranean countries such as …

Is Sickle Cell more common in males or females?

The incidence of sickle cell disease is not gender-related since it is transmitted as an autosomal recessive disorder. However, there have been reports of sex related differences in SCD mortality and morbidity in adult patients.