In Remnant 2, you will face the most horrible enemies at every stage of your progression. You will have to try out a dozen offensive strategies to pass them, which you will easily discover as your game sense increases. But the point is that you also have to focus on your defense to improve your survival. And as far as I know, equipping the Best Armor Set is an ideal way to do that.
Remnant 2 – Unlock the SECRET Alchemist Class Fast! Secret Archetype, Armor, and Weapon Guide
While we're on the subject, there are 20+ Armor Sets available in Remnant 2, including the Awakened King DLC. So you know that picking the perfect set takes a lot of time. But since I know you don't have much time to spare, we've made this list.
Despite being an Ultra Heavy Armor Set with a higher Stamina Cost, Leto Mark II set is an exceptional choice to boost your defense. This S-Tier Armor Set offers protection from all types of damage. However, the cost for this is limited mobility. Yes, and if you want to tackle it, then equipping an Amulet like Rusted Navigator's Pendant will help you a lot.
From what I have seen, the Leto Mark II Armor Set is best suited for the Challenger Class. That is because a Challenger has to fight in close quarters. They are susceptible to enemy attacks all the time. So to withstand all that damage and give it back to the enemies, I think the Leto Mark II Armor is best suited for a Challenger.