Yoko Hiromine is the new character who drastically changes the story of Shin Megami Tensei V: Vengeance if you choose the Canon of Vengeance path. However, her philosophy is questionable and players continue to make fun of it.
Shin Megami Tensei V: Vengeance – Opening Movie
Yoko serves as a thematic counterpoint to Tao; she prefers chaos over order, seeing order as maintaining a status quo in which many people suffer. The philosophical battle between chaos and order defines the Shin Megami Tensei series, and many SMT games present solid arguments for and against both sides. There's nothing wrong with this, but the way Yoko expresses her opinions has made her the center of Shin Megami Tensei V: Vengeance memes.
Early in Shin Megami Tensei V: Vengeance, Yoko responds to Amanozako's curiosity about cars by saying that they should never have existed because millions of people have died in them. Some players agree with her, saying, "She's right. A little extreme, but she's right," while another commenter sarcastically calls her the "Least unhinged chaos rep."
Her "anti-car" monologue immediately draws comparisons to Takaya in Persona 3 Reload, who has a similar moment where he asks the protagonist why he's fighting Shadows when 5,000 people die in car accidents in Japan every year. One commentator says, "Persona has Takaya, SMT has Yoko. Metaphor: ReFantazio needs a character who hates cars, and the trilogy is complete."