There's funny, there's very funny, and then there's Oh, Mary!, Cole Escola's insurgent new comedy that brings more laughs to Broadway than all the Gutenbergs, Edelmans, and Birbiglias combined. You can throw in Shucked for good measure.

Escola, quietly famous in recent years for YouTube videos, late-night performances and appearances on TV's The Other Two and Difficult People , ups the career stakes big time with Oh, Mary!, opening tonight at Broadway's Lyceum Theatre. With nods and nods to Charles Busch, the late, great and forever Ridiculous Everett Quinton, the Sedaris siblings, Carol Burnett, Pee-wee Herman and Absolutely Fabulous, Escola squeezes just enough juice from their influences for a mix that's utterly fresh and unmissable.

After its acclaimed, sold-out run Off Broadway at the Lucille Lortel Theatre, Oh, Mary!, directed by Sam Pinkleton, wastes no time in arriving on Broadway with its unflinching queerness and brazen vulgarity intact. Yes, this low-tech, 80-minute production has Broadway ticket prices, but that fact should only get in the way until the first round of laughter unleashes it.

Featuring Escola dressed in Mary Todd Lincoln’s famous black dress and curly hair, Oh, Mary! is a wildly campy take on the classic House Divided. A few houses, to be exact.